TY - JOUR
T1 - Lymphatic malformations
T2 - Review of current treatment
AU - Perkins, Jonathan A.
AU - Manning, Scott C.
AU - Tempero, Richard M.
AU - Cunningham, Michael J.
AU - Edmonds, Joseph L.
AU - Hoffer, Fredric A.
AU - Egbert, Mark A.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2010/6
Y1 - 2010/6
N2 - Objective: Summarize current knowledge of lymphatic malformation medical, sclerotherapy, and surgical treatment; and highlight areas of treatment controversy and treatment difficulty that need improvement. Methods: Panel presentation of various aspects of lymphatic malformation treatment. Results: The mainstay of lymphatic malformation treatment has been surgical resection, which has been refined through lesion staging and radiographic characterization. Intralesional sclerotherapy in macrocystic lymphatic malformations is effective. Suprahyoid microcystic lymphatic malformations are more difficult to treat than macrocystic lymphatic malformations in the infrahyoid and posterior cervical regions. Bilateral suprahyoid lymphatic malformations require staged treatment to prevent complications. Lymphatic malformation treatment planning is primarily determined by the presence or possibility of functional compromise. Problematic areas include chronic lymphatic malformation inflammation, dental health maintenance, macroglossia, airway obstruction, and dental malocclusion. Conclusions: Lymphatic malformation treatment improvements have been made through radiographic characterization and staging of lymphatic malformations. Direct malformation involvement of the upper aerodigestive tract can cause significant functional compromise that is difficult to treat.
AB - Objective: Summarize current knowledge of lymphatic malformation medical, sclerotherapy, and surgical treatment; and highlight areas of treatment controversy and treatment difficulty that need improvement. Methods: Panel presentation of various aspects of lymphatic malformation treatment. Results: The mainstay of lymphatic malformation treatment has been surgical resection, which has been refined through lesion staging and radiographic characterization. Intralesional sclerotherapy in macrocystic lymphatic malformations is effective. Suprahyoid microcystic lymphatic malformations are more difficult to treat than macrocystic lymphatic malformations in the infrahyoid and posterior cervical regions. Bilateral suprahyoid lymphatic malformations require staged treatment to prevent complications. Lymphatic malformation treatment planning is primarily determined by the presence or possibility of functional compromise. Problematic areas include chronic lymphatic malformation inflammation, dental health maintenance, macroglossia, airway obstruction, and dental malocclusion. Conclusions: Lymphatic malformation treatment improvements have been made through radiographic characterization and staging of lymphatic malformations. Direct malformation involvement of the upper aerodigestive tract can cause significant functional compromise that is difficult to treat.
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U2 - 10.1016/j.otohns.2010.02.026
DO - 10.1016/j.otohns.2010.02.026
M3 - Article
C2 - 20493348
AN - SCOPUS:77952253212
SN - 0194-5998
VL - 142
SP - 795-803.e1
JO - Otolaryngology - Head and Neck Surgery
JF - Otolaryngology - Head and Neck Surgery
IS - 6
ER -