Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template

Yueteng Wei; Ru Liu; Zhipeng Sun; Yaling Wang; Yanyan Cui; Yuliang Zhao; Zhifang Cai; Xueyun Gao

doi:10.1039/c3an36689h

Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template

Yueteng Wei, Ru Liu, Zhipeng Sun, Yaling Wang, Yanyan Cui, Yuliang Zhao, Zhifang Cai, Xueyun Gao

Houston Methodist

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Luminescent silver nanoclusters were anchored by designed oligonucleotides. After hybridizing with human telomerase RNA template, the luminescence of the cluster decreased linearly with respect to the concentration of the complementary strand (25-250 nM). The cluster is therefore a potential candidate for human telomerase detection.

Original language	English (US)
Pages (from-to)	1338-1341
Number of pages	4
Journal	Analyst
Volume	138
Issue number	5
DOIs	https://doi.org/10.1039/c3an36689h
State	Published - Mar 7 2013

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Environmental Chemistry
Spectroscopy
Electrochemistry

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title = "Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template",

abstract = "Luminescent silver nanoclusters were anchored by designed oligonucleotides. After hybridizing with human telomerase RNA template, the luminescence of the cluster decreased linearly with respect to the concentration of the complementary strand (25-250 nM). The cluster is therefore a potential candidate for human telomerase detection.",

author = "Yueteng Wei and Ru Liu and Zhipeng Sun and Yaling Wang and Yanyan Cui and Yuliang Zhao and Zhifang Cai and Xueyun Gao",

year = "2013",

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T1 - Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template

AU - Wei, Yueteng

AU - Liu, Ru

AU - Sun, Zhipeng

AU - Wang, Yaling

AU - Cui, Yanyan

AU - Zhao, Yuliang

AU - Cai, Zhifang

AU - Gao, Xueyun

PY - 2013/3/7

Y1 - 2013/3/7

N2 - Luminescent silver nanoclusters were anchored by designed oligonucleotides. After hybridizing with human telomerase RNA template, the luminescence of the cluster decreased linearly with respect to the concentration of the complementary strand (25-250 nM). The cluster is therefore a potential candidate for human telomerase detection.

AB - Luminescent silver nanoclusters were anchored by designed oligonucleotides. After hybridizing with human telomerase RNA template, the luminescence of the cluster decreased linearly with respect to the concentration of the complementary strand (25-250 nM). The cluster is therefore a potential candidate for human telomerase detection.

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DO - 10.1039/c3an36689h

M3 - Article

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EP - 1341

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Luminescent silver nanoclusters anchored by oligonucleotides detect human telomerase ribonucleic acid template

Abstract

ASJC Scopus subject areas

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