TY - JOUR
T1 - Lower Interobserver Reliability for Nondimensional Intracystic Features Among Abdominal Radiologists for Characterizing Intraductal Papillary Mucinous Neoplasms Using Magnetic Resonance Imaging
AU - Scherer, John A.
AU - Gebhard, Robyn
AU - Firkins, Stephen A.
AU - Shah, Zarine K.
AU - Urbina Andersson, Irma K.
AU - Barker, Samantha J.
AU - Fiorillo, Lauren E.
AU - Hollander, Ephraim
AU - Shaheen, Nicholas
AU - Koay, Eugene J.
AU - Conwell, Darwin L.
AU - Krishna, Somashekar G.
N1 - Funding Information:
S.G.K. is the principal investigator (PI) of an investigator-initiated study. The study in part is a funded by a grant to The Ohio State University Wexner Medical Center from Mauna Kea Technologies, Paris, France.
Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2022/10/1
Y1 - 2022/10/1
N2 - Objectives Current guidelines recommend magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP) for risk stratification of intraductal papillary mucinous neoplasms (IPMNs). We assessed the interobserver agreement among radiologists in evaluating and risk stratifying IPMNs. Methods This single-center study evaluated 30 patients with IPMNs who had undergone MRI/MRCP, endoscopic ultrasound, and/or surgical resection. Six abdominal radiologists evaluated the MRI/MRCPs to document multiple parameters. The analysis applied Landis and Koch κ interpretation for categorical variables and intraclass correlation coefficient (r) for continuous variables. Results Radiologists demonstrated almost perfect agreement for location (κ = 0.81, 95% confidence interval [CI], 0.74-0.87), size (r = 0.95; 95% CI, 0.89-0.98), and main pancreatic duct diameter (r = 0.98; 95% CI, 0.96-0.99). Substantial agreement was observed for communication with the main pancreatic duct (κ = 0.66; 95% CI, 0.57-0.75) and classification of IPMN subtype (κ = 0.77; 95% CI, 0.67-0.86). Presence of intracystic nodules (κ = 0.31; 95% CI, 0.21-0.42) and wall thickening (κ = 0.09; 95% CI, -0.01 to 0.18) reached only fair and slight agreement, respectively. Conclusions Although MRI/MRCP is excellent in the evaluation of spatial aspects, there is lower reliability for nondimensional characteristics of IPMNs. These data support guideline-recommended complementary evaluation of IPMNs with MRI/MRCP and endoscopic ultrasound.
AB - Objectives Current guidelines recommend magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP) for risk stratification of intraductal papillary mucinous neoplasms (IPMNs). We assessed the interobserver agreement among radiologists in evaluating and risk stratifying IPMNs. Methods This single-center study evaluated 30 patients with IPMNs who had undergone MRI/MRCP, endoscopic ultrasound, and/or surgical resection. Six abdominal radiologists evaluated the MRI/MRCPs to document multiple parameters. The analysis applied Landis and Koch κ interpretation for categorical variables and intraclass correlation coefficient (r) for continuous variables. Results Radiologists demonstrated almost perfect agreement for location (κ = 0.81, 95% confidence interval [CI], 0.74-0.87), size (r = 0.95; 95% CI, 0.89-0.98), and main pancreatic duct diameter (r = 0.98; 95% CI, 0.96-0.99). Substantial agreement was observed for communication with the main pancreatic duct (κ = 0.66; 95% CI, 0.57-0.75) and classification of IPMN subtype (κ = 0.77; 95% CI, 0.67-0.86). Presence of intracystic nodules (κ = 0.31; 95% CI, 0.21-0.42) and wall thickening (κ = 0.09; 95% CI, -0.01 to 0.18) reached only fair and slight agreement, respectively. Conclusions Although MRI/MRCP is excellent in the evaluation of spatial aspects, there is lower reliability for nondimensional characteristics of IPMNs. These data support guideline-recommended complementary evaluation of IPMNs with MRI/MRCP and endoscopic ultrasound.
KW - interobserver variability
KW - intraductal papillary mucinous neoplasm
KW - magnetic resonance cholangiopancreatography
KW - magnetic resonance imaging
KW - pancreas
KW - pancreas cyst
UR - http://www.scopus.com/inward/record.url?scp=85153414429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85153414429&partnerID=8YFLogxK
U2 - 10.1097/MPA.0000000000002174
DO - 10.1097/MPA.0000000000002174
M3 - Article
C2 - 37078949
AN - SCOPUS:85153414429
VL - 51
SP - 1225
EP - 1230
JO - Pancreas
JF - Pancreas
SN - 0885-3177
IS - 9
ER -