Low-grade myofibroblastic sarcoma of the sacrum: Case report

William E. Humphries, Krishna B. Satyan, Katherine Relyea, Eugene S. Kim, Adekunle M. Adesina, Murali Chintagumpala, Andrew Jea

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Myofibroblastic tumors are soft-tissue neoplasms arising from myofibroblasts, ubiquitous cells sharing ultrastructural features of muscular and fibroblastic cells. Vasudev and Harris described a malignant counterpart of these benign tumors in 1978. Most reported cases of myofibroblastic sarcoma have arisen in the head and neck region and the soft tissues of the extremities. To the best of the authors' knowledge, there have been only 8 previous reports on primary myofibroblastic sarcoma of the bone. The authors report a new case of this rare tumor affecting the sacrum and ilium of a 15-year-old girl and discuss the role of total sacrectomy and lumbopelvic reconstruction for treatment of this disease.

Original languageEnglish (US)
Pages (from-to)286-290
Number of pages5
JournalJournal of Neurosurgery: Pediatrics
Issue number3
StatePublished - Sep 2010


  • Myofibroblastic sarcoma
  • Pediatric spine
  • Sacrectomy

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Pediatrics, Perinatology, and Child Health


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