TY - JOUR
T1 - Longitudinal magnetic resonance findings in delayed posthypoxic leukoencephalopathy
AU - Phan, Mimi N.
AU - Nakawah, Mohammad Obadah
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Delayed posthypoxic leukoencephalopathy is a rare condition that can occur following prolonged cerebral hypo-oxygenation and manifests as acute onset of neuropsychiatric symptoms after a period of apparent recovery. We describe a case of a 76-year-old man who presented after an unwitnessed fall of unknown duration with initial recovery followed by progressive neurocognitive decline resulting in dementia, dysphasia, and gait apraxia. Initial brain magnetic resonance imaging was unremarkable but repeated brain imaging revealed progressive leukoencephalopathy, which started as small foci of abnormal diffusion restriction in bilateral frontal lobes and gradually evolved over the next 3 weeks to diffuse signal changes in the white matter.
AB - Delayed posthypoxic leukoencephalopathy is a rare condition that can occur following prolonged cerebral hypo-oxygenation and manifests as acute onset of neuropsychiatric symptoms after a period of apparent recovery. We describe a case of a 76-year-old man who presented after an unwitnessed fall of unknown duration with initial recovery followed by progressive neurocognitive decline resulting in dementia, dysphasia, and gait apraxia. Initial brain magnetic resonance imaging was unremarkable but repeated brain imaging revealed progressive leukoencephalopathy, which started as small foci of abnormal diffusion restriction in bilateral frontal lobes and gradually evolved over the next 3 weeks to diffuse signal changes in the white matter.
KW - Delayed posthypoxic leukoencephalopathy
KW - diffusion restriction
KW - magnetic resonance imaging
KW - parkinsonism
UR - http://www.scopus.com/inward/record.url?scp=85087944803&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85087944803&partnerID=8YFLogxK
U2 - 10.1080/08998280.2020.1778423
DO - 10.1080/08998280.2020.1778423
M3 - Article
AN - SCOPUS:85087944803
VL - 33
SP - 679
EP - 680
JO - Baylor University Medical Center Proceedings
JF - Baylor University Medical Center Proceedings
SN - 0899-8280
IS - 4
ER -