Longitudinal magnetic resonance findings in delayed posthypoxic leukoencephalopathy

Research output: Contribution to journalArticle

Abstract

Delayed posthypoxic leukoencephalopathy is a rare condition that can occur following prolonged cerebral hypo-oxygenation and manifests as acute onset of neuropsychiatric symptoms after a period of apparent recovery. We describe a case of a 76-year-old man who presented after an unwitnessed fall of unknown duration with initial recovery followed by progressive neurocognitive decline resulting in dementia, dysphasia, and gait apraxia. Initial brain magnetic resonance imaging was unremarkable but repeated brain imaging revealed progressive leukoencephalopathy, which started as small foci of abnormal diffusion restriction in bilateral frontal lobes and gradually evolved over the next 3 weeks to diffuse signal changes in the white matter.

Original languageEnglish (US)
Pages (from-to)679-680
Number of pages2
JournalBaylor University Medical Center Proceedings
Volume33
Issue number4
DOIs
StatePublished - Oct 1 2020

Keywords

  • Delayed posthypoxic leukoencephalopathy
  • diffusion restriction
  • magnetic resonance imaging
  • parkinsonism

ASJC Scopus subject areas

  • Medicine(all)

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