Long-term monitoring of gait in Parkinson's disease

Steven T. Moore, Hamish G. MacDougall, Jean Michel Gracies, Helen S. Cohen, William G. Ondo

Research output: Contribution to journalArticle

147 Scopus citations

Abstract

A new system for long-term monitoring of gait in Parkinson's disease (PD) has been developed and validated. The characteristics of every stride taken over 10-h epochs were acquired using a lightweight ankle-mounted sensor array that transmitted data wirelessly to a small pocket PC at a rate of 100 Hz. Stride was calculated from the vertical linear acceleration and pitch angular velocity of the leg with an accuracy of 5 cm. Results from PD patients (5) demonstrate the effectiveness of long-term monitoring of gait in a natural environment. The small, variable stride length characteristic of Parkinsonian gait, and fluctuations of efficacy associated with levodopa therapy, such as delayed onset, wearing off, and the 'off/on' effect, could reliably be detected from long-term changes in stride length.

Original languageEnglish (US)
Pages (from-to)200-207
Number of pages8
JournalGait and Posture
Volume26
Issue number2
DOIs
StatePublished - Jul 1 2007

Keywords

  • Accelerometer
  • Levodopa
  • Locomotion
  • Parkinsonian
  • Stride length

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Rehabilitation

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