Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Eugene C. Lai; J. Jankovic; J. K. Krauss; William G. Ondo; Robert G. Grossman

doi:10.1212/WNL.55.8.1218

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Eugene C. Lai, J. Jankovic, J. K. Krauss, William G. Ondo, Robert G. Grossman

Research output: Contribution to journal › Article › peer-review

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Abstract

The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).

Original language	English (US)
Pages (from-to)	1218-1222
Number of pages	5
Journal	Neurology
Volume	55
Issue number	8
DOIs	https://doi.org/10.1212/WNL.55.8.1218
State	Published - Oct 24 2000

ASJC Scopus subject areas

Clinical Neurology

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abstract = "The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).",

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AU - Jankovic, J.

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AU - Ondo, William G.

AU - Grossman, Robert G.

PY - 2000/10/24

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N2 - The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).

AB - The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).

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Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Abstract

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