Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Eugene C. Lai; J. Jankovic; J. K. Krauss; William G. Ondo; Robert G. Grossman

doi:10.1212/WNL.55.8.1218

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Eugene C. Lai, J. Jankovic, J. K. Krauss, William G. Ondo, Robert G. Grossman

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).

Original language	English (US)
Pages (from-to)	1218-1222
Number of pages	5
Journal	Neurology
Volume	55
Issue number	8
DOIs	https://doi.org/10.1212/WNL.55.8.1218
State	Published - Oct 24 2000

ASJC Scopus subject areas

Clinical Neurology

Access to Document

10.1212/WNL.55.8.1218

Cite this

@article{16b1c82f37f84478ab237ef8a551a4bb,

title = "Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease",

abstract = "The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).",

author = "Lai, {Eugene C.} and J. Jankovic and Krauss, {J. K.} and Ondo, {William G.} and Grossman, {Robert G.}",

year = "2000",

month = oct,

day = "24",

doi = "10.1212/WNL.55.8.1218",

language = "English (US)",

volume = "55",

pages = "1218--1222",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

number = "8",

}

TY - JOUR

T1 - Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

AU - Lai, Eugene C.

AU - Jankovic, J.

AU - Krauss, J. K.

AU - Ondo, William G.

AU - Grossman, Robert G.

PY - 2000/10/24

Y1 - 2000/10/24

N2 - The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).

AB - The authors describe results of unilateral posteroventral pallidotomy (PVP) in 89 patients with PD. At 3 months after surgery, 81.9% of the patients reported marked or moderate improvement in their parkinsonian symptoms. Postoperative Unified PD Rating Scale 'off' state mean total motor score improved by 35.5% and the mean activities of daily living score by 33.7% (p < 0.001). Improvements in parkinsonian symptoms were maintained in both 'off' and 'on' states in 62 patients at 12 months after PVP and in 41 patients who were followed for 18 months or longer (mean 26.6 months).

UR - http://www.scopus.com/inward/record.url?scp=0034711148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034711148&partnerID=8YFLogxK

U2 - 10.1212/WNL.55.8.1218

DO - 10.1212/WNL.55.8.1218

M3 - Article

C2 - 11071505

AN - SCOPUS:0034711148

VL - 55

SP - 1218

EP - 1222

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 8

ER -

Long-term efficacy of posteroventral pallidotomy in the treatment of Parkinson's disease

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this