Localized cecal zygomycosis following renal transplantation

Zygomycosis occurs as an opportunistic infection following organ transplantation and immunosuppressive therapy. Gastrointestinal zygomycosis is an exceedingly rare and usually fatal presentation of this infection. We discuss the case of a renal transplant recipient who survived cecal perforation from zygomycosis. The successful treatment consisted of aggressive surgical resection, intensive course of antifungal therapy, and rapid withdrawal of anti-rejection medications.