Abstract
The chromosomal location of the murine macrophage colony-stimulating factor (Csfm) gene was determined by interspecific backcross analysis. We mapped Csfm to mouse chromosome 3, 2.5 cM distal to Ngfb and Nras and 1.3 cM proximal to Amy-2. CSFM maps to human chromosome 5q, while AMY2, NGFB, and NRAS map to human chromosome 1p. The chromosomal location of Csfm thus disrupts a previously identified conserved linkage group between mouse chromosome 3 and human chromosome 1. The location of Csfm also identifies yet another mouse chromosome that shares synteny with human chromosome 5q, a region involved in several different types of myeloid disease.
Original language | English (US) |
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Pages (from-to) | 363-367 |
Number of pages | 5 |
Journal | Genomics |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - Aug 1989 |
ASJC Scopus subject areas
- Genetics