Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting

Judith A. Cebra-Thomas; Jen Yue Tsai; Stephen H. Pilder; Neal G. Copeland; Nancy A. Jenkins; Lee M. Silver

doi:10.1016/0888-7543(92)90267-V

Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting

Judith A. Cebra-Thomas, Jen Yue Tsai, Stephen H. Pilder, Neal G. Copeland, Nancy A. Jenkins, Lee M. Silver

Research output: Contribution to journal › Article › peer-review

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Abstract

The mouse homolog of the human proto-oncogene MAS was mapped by two interspecific backcrosses to the proximal portion of MMU 17. Higher resolution mapping was accomplished through the analysis of genotypes duplicated or deleted for a megabase-size subregion within MMU 17. The results demonstrate a map position for Mas in the close vicinity of Igf2r, which encodes another membrane receptor known to undergo genomic imprinting. The data provide further evidence for the clustering of genes in a 1-Mb region of chromosome 17, with the absence of any identified genes in a nearby region likely to be six times larger.

Original language	English (US)
Pages (from-to)	444-446
Number of pages	3
Journal	Genomics
Volume	13
Issue number	2
DOIs	https://doi.org/10.1016/0888-7543(92)90267-V
State	Published - Jun 1992

ASJC Scopus subject areas

Genetics

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10.1016/0888-7543(92)90267-V

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title = "Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting",

abstract = "The mouse homolog of the human proto-oncogene MAS was mapped by two interspecific backcrosses to the proximal portion of MMU 17. Higher resolution mapping was accomplished through the analysis of genotypes duplicated or deleted for a megabase-size subregion within MMU 17. The results demonstrate a map position for Mas in the close vicinity of Igf2r, which encodes another membrane receptor known to undergo genomic imprinting. The data provide further evidence for the clustering of genes in a 1-Mb region of chromosome 17, with the absence of any identified genes in a nearby region likely to be six times larger.",

author = "Cebra-Thomas, {Judith A.} and Tsai, {Jen Yue} and Pilder, {Stephen H.} and Copeland, {Neal G.} and Jenkins, {Nancy A.} and Silver, {Lee M.}",

note = "Funding Information: was supported by grants Cancer Institute, DHHS, (N.G.C. and N.A.J.). Funding Information: from the NIH to L.M.S. and under Contract NOl-CO- Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1992",

month = jun,

doi = "10.1016/0888-7543(92)90267-V",

language = "English (US)",

volume = "13",

pages = "444--446",

journal = "Genomics",

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publisher = "Academic Press",

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T1 - Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting

AU - Cebra-Thomas, Judith A.

AU - Tsai, Jen Yue

AU - Pilder, Stephen H.

AU - Copeland, Neal G.

AU - Jenkins, Nancy A.

AU - Silver, Lee M.

N1 - Funding Information: was supported by grants Cancer Institute, DHHS, (N.G.C. and N.A.J.). Funding Information: from the NIH to L.M.S. and under Contract NOl-CO- Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1992/6

Y1 - 1992/6

N2 - The mouse homolog of the human proto-oncogene MAS was mapped by two interspecific backcrosses to the proximal portion of MMU 17. Higher resolution mapping was accomplished through the analysis of genotypes duplicated or deleted for a megabase-size subregion within MMU 17. The results demonstrate a map position for Mas in the close vicinity of Igf2r, which encodes another membrane receptor known to undergo genomic imprinting. The data provide further evidence for the clustering of genes in a 1-Mb region of chromosome 17, with the absence of any identified genes in a nearby region likely to be six times larger.

AB - The mouse homolog of the human proto-oncogene MAS was mapped by two interspecific backcrosses to the proximal portion of MMU 17. Higher resolution mapping was accomplished through the analysis of genotypes duplicated or deleted for a megabase-size subregion within MMU 17. The results demonstrate a map position for Mas in the close vicinity of Igf2r, which encodes another membrane receptor known to undergo genomic imprinting. The data provide further evidence for the clustering of genes in a 1-Mb region of chromosome 17, with the absence of any identified genes in a nearby region likely to be six times larger.

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Localization of the Mas proto-oncogene to a densely marked region of mouse chromosome 17 associated with genomic imprinting

Abstract

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