Abstract
Atherosclerosis is a complex process responsible for a major burden of cardiovascular morbidity and mortality. Macrophages and smooth muscle cells (SMCs) are abundant within atherosclerotic plaques. This review discusses the role of macrophages and SMCs in plaque progression and provides an overview of nanoparticle-based approaches and other current methods for local targeting of atherosclerotic plaques.
Original language | English (US) |
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Pages (from-to) | 141-145 |
Number of pages | 5 |
Journal | Methodist DeBakey cardiovascular journal |
Volume | 12 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2016 |
Keywords
- atherosclerosis
- macrophage
- nanoparticle
- nanotechnology
- plaque
- smooth muscle cell
ASJC Scopus subject areas
- General Medicine