Lipomatosis coli, a mimicker of familial polyposis

Neda Zarrin-Khameh, Eric M. Haas, Jae Ro, Michael J. Thrall

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Multiple intestinal lipomas (lipomatous polyposis) are quite rare, and they can be quite challenging to diagnose because this condition may be clinically confused with familial adenomatous polyposis with a suggestive family history. Herein, we present a case of lipomatous polyposis that was presented with abdominal pain and, in colonoscopy, had more than 100 polyps. The patient was admitted for surgery with diagnosis of familial polyposis. Resected colon specimen had multiple polyps ranging from 0.1 to 1.5 cm. Microscopically, the polyps were composed of mature adipose tissue with normal overlying mucosa. There were also increased fat cells in the submucosa of the colon adjacent to the polyps. Lipomatous polyposis rarely occurs and can be confused with familial polyposis. Polypectomy is a simple and cost-effective procedure to help in diagnosis and prevent a major surgery.

Original languageEnglish (US)
Pages (from-to)210-213
Number of pages4
JournalAnnals of Diagnostic Pathology
Issue number2
StatePublished - Apr 2013


  • Lipomatosis coli

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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