Lipase Elevation in Patients with COVID-19

Julia McNabb-Baltar; David X. Jin; Amit S. Grover; Walker D. Redd; Joyce C. Zhou; Kelly E. Hathorn; Thomas R. McCarty; Ahmad N. Bazarbashi; Lin Shen; Walter W. Chan

doi:10.14309/ajg.0000000000000732

Lipase Elevation in Patients with COVID-19

Julia McNabb-Baltar, David X. Jin, Amit S. Grover, Walker D. Redd, Joyce C. Zhou, Kelly E. Hathorn, Thomas R. McCarty, Ahmad N. Bazarbashi, Lin Shen, Walter W. Chan

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19.METHODS:A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19.RESULTS:Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms.DISCUSSION:Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.

Original language	English (US)
Pages (from-to)	1286-1288
Number of pages	3
Journal	American Journal of Gastroenterology
Volume	115
Issue number	8
DOIs	https://doi.org/10.14309/ajg.0000000000000732
State	Published - Aug 1 2020

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.14309/ajg.0000000000000732

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title = "Lipase Elevation in Patients with COVID-19",

abstract = "Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19.METHODS:A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19.RESULTS:Of 71 patients, 9 (12.1\%) developed hyperlipasemia, with 2 (2.8\%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms.DISCUSSION:Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.",

author = "Julia McNabb-Baltar and Jin, \{David X.\} and Grover, \{Amit S.\} and Redd, \{Walker D.\} and Zhou, \{Joyce C.\} and Hathorn, \{Kelly E.\} and McCarty, \{Thomas R.\} and Bazarbashi, \{Ahmad N.\} and Lin Shen and Chan, \{Walter W.\}",

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T1 - Lipase Elevation in Patients with COVID-19

AU - McNabb-Baltar, Julia

AU - Jin, David X.

AU - Grover, Amit S.

AU - Redd, Walker D.

AU - Zhou, Joyce C.

AU - Hathorn, Kelly E.

AU - McCarty, Thomas R.

AU - Bazarbashi, Ahmad N.

AU - Shen, Lin

AU - Chan, Walter W.

PY - 2020/8/1

Y1 - 2020/8/1

N2 - Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19.METHODS:A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19.RESULTS:Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms.DISCUSSION:Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.

AB - Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19.METHODS:A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19.RESULTS:Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms.DISCUSSION:Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.

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Lipase Elevation in Patients with COVID-19

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