TY - JOUR
T1 - Life expectancy after Mohs micrographic surgery in patients aged 90 years and older
AU - Delaney, Amy
AU - Shimizu, Ikue
AU - Goldberg, Leonard H.
AU - MacFarlane, Deborah F.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013/2
Y1 - 2013/2
N2 - Background: The population of people aged 90 years and older is expected to more than triple by 2050. The incidence of skin cancers is increasing. Objective: We sought to determine whether treatment of patients aged 90 years and older with skin cancer by Mohs micrographic surgery (MMS) changed their survival. Methods: A group of 214 patients aged 90 years and older who underwent MMS from July 1997 to May 2006 was identified. Patient gender, age, tumor type, size, site, defect size, number of MMS stages, and surgical repair were recorded. Comorbid medical conditions were assessed using the Charlson index. Actual survival was compared with expected length of survival using life tables. Data were analyzed by the Kaplan-Meier method with log rank significance tests. Results: Average patient age was 92.3 years. All patients tolerated the procedures well with no deaths within 1 month after surgery. Median survival after surgery was 36.9 months. Tumor characteristics, defect size, number of surgical stages, and closure type did not affect survival. There was no significant difference in survival based on comorbidities according to Charlson scores. Instantaneous mortality hazard was highest 2 to 3 years after surgery. Limitations: Specific causes of death were not accessible. Conclusion: This growing section of the population may safely undergo MMS.
AB - Background: The population of people aged 90 years and older is expected to more than triple by 2050. The incidence of skin cancers is increasing. Objective: We sought to determine whether treatment of patients aged 90 years and older with skin cancer by Mohs micrographic surgery (MMS) changed their survival. Methods: A group of 214 patients aged 90 years and older who underwent MMS from July 1997 to May 2006 was identified. Patient gender, age, tumor type, size, site, defect size, number of MMS stages, and surgical repair were recorded. Comorbid medical conditions were assessed using the Charlson index. Actual survival was compared with expected length of survival using life tables. Data were analyzed by the Kaplan-Meier method with log rank significance tests. Results: Average patient age was 92.3 years. All patients tolerated the procedures well with no deaths within 1 month after surgery. Median survival after surgery was 36.9 months. Tumor characteristics, defect size, number of surgical stages, and closure type did not affect survival. There was no significant difference in survival based on comorbidities according to Charlson scores. Instantaneous mortality hazard was highest 2 to 3 years after surgery. Limitations: Specific causes of death were not accessible. Conclusion: This growing section of the population may safely undergo MMS.
KW - basal cell carcinoma
KW - Mohs micrographic surgery
KW - nonagenarian
KW - perioperative mortality
KW - perioperative safety
KW - squamous cell carcinoma
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U2 - 10.1016/j.jaad.2012.10.016
DO - 10.1016/j.jaad.2012.10.016
M3 - Article
C2 - 23200199
AN - SCOPUS:84872360164
VL - 68
SP - 296
EP - 300
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 2
ER -