Latent profile analyses of posttraumatic stress disorder, depression and generalized anxiety disorder symptoms in trauma-exposed soldiers

Ateka A. Contractor, Jon D. Elhai, Thomas H. Fine, Marijo B. Tamburrino, Gregory Cohen, Edwin Shirley, Philip K. Chan, Israel Liberzon, Sandro Galea, Joseph R. Calabrese

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

Posttraumatic stress disorder (PTSD) is comorbid with major depressive disorder (MDD; Kessler et al., 1995) and generalized anxiety disorder (GAD; Brown et al., 2001). We aimed to (1) assess discrete patterns of post-trauma PTSD-depression-GAD symptoms using latent profile analyses (LPAs), and (2)assess covariates (gender, income, education, age) in defining the best fitting class solution. The PTSD Checklist (assessing PTSD symptoms), GAD-7 scale (assessing GAD symptoms), and Patient Health Questionnaire-9 (assessing depression) were administered to 1266 trauma-exposed Ohio National Guard soldiers. Results indicated three discrete subgroups based on symptom patterns with mild (class 1), moderate (class 2) and severe (class 3) levels of symptomatology. Classes differed in symptom severity rather than symptom type. Income and education significantly predicted class 1 versus class 3 membership, and class 2 versus class 3. In conclusion, there is heterogeneity regarding severity of PTSD-depression-GAD symptomatology among trauma-exposed soldiers, with income and education predictive of class membership.

Original languageEnglish (US)
Pages (from-to)19-26
Number of pages8
JournalJournal of Psychiatric Research
Volume68
DOIs
StatePublished - Sep 1 2015

Keywords

  • Depression
  • GAD
  • Latent profile analyses
  • PTSD
  • Trauma-exposed soldiers

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Fingerprint Dive into the research topics of 'Latent profile analyses of posttraumatic stress disorder, depression and generalized anxiety disorder symptoms in trauma-exposed soldiers'. Together they form a unique fingerprint.

Cite this