Large cell calcifying Sertoli cell tumor of the testis: A clinicopathologic, immunohistochemical, and ultrastructural study of two cases

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Abstract

The clinicopathologic, immunohistochemical, and electron microscopic study of two patients with large cell calcifying Sertoli cell tumors (LCCSCT) of the testis is reported to elucidate the histogenesis of this rare tumor. Both tumors occurred in young individuals (16 and 32 years); case 1 was found incidentally, and the patient in case 2 presented with a 3-4-week history of testicular pain. Evidence of testosterone production was demonstrated in one case. In the same case, at the ultrastructural level Charcot-Bottcher crystalloids were observed. These data support previous reports that LCCSCT shows Sertoli cell differentiation.

Original languageEnglish (US)
Pages (from-to)717-722
Number of pages6
JournalAmerican Journal of Clinical Pathology
Volume96
Issue number6
DOIs
StatePublished - Jan 1 1991

Keywords

  • Charcot-Bottcher crystalloids
  • Sertoli cell tumor
  • Stromal cell tumor
  • Testicular neoplasm

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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