Laboratory and clinical aspects of inherited thrombotic disorders

George M. Rodgers, Wayne Chandler

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

The laboratory evaluation of patients with recurrent thrombosis is frequently frustrating, with a low diagnostic yield obtained despite extensive testing. The likelihood of reaching a diagnosis in these patients can be increased by considering diagnostic possibilities usually overlooked and by using assays optimal for their detection. This review summarizes clinical and laboratory issues important in inherited thrombotic disease and discusses practical aspects and a strategy for laboratory testing. New information is provided on the fibrinolytic disorders that may be a common cause of recurrent thrombosis.

Original languageEnglish (US)
Pages (from-to)113-122
Number of pages10
JournalAmerican Journal of Hematology
Volume41
Issue number2
DOIs
StatePublished - Jan 1 1992

Keywords

  • antithrombin III
  • dysfibrinogenemia
  • fibrinolysis
  • homocystinuria
  • protein C
  • protein S

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Laboratory and clinical aspects of inherited thrombotic disorders'. Together they form a unique fingerprint.

Cite this