Abstract
An immunohistochemical method, followed by silvering (Ag-treatment) of the final product of peroxidase reaction for N7-methylguanine detection, was first employed for human cells treated in vitro with N-methylnitrosourea. This method appeared to be highly specific and sensitive, compared to the routine immunohistochemical technique. Evidence has been provided on the application of Ag-treatment for detecting N7-methylguanine in the esophagus epithelium of patients with a high risk of cancer with this particular locality.
| Translated title of the contribution | The use of an immunohistochemical method for detecting N7-methylguanine in human cells |
|---|---|
| Original language | Russian |
| Pages (from-to) | 57-61 |
| Number of pages | 5 |
| Journal | Tsitologiya |
| Volume | 34 |
| Issue number | 3 |
| State | Published - Jan 1 1992 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology