TY - JOUR
T1 - Irreversible Renal Failure Following Vesicoureteral Reflux
AU - Senekjian, Harry O.
AU - Stinebaugh, Bobby J.
AU - Suki, Wadi N.
AU - Mattioli, Carlos A.
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1979/1/12
Y1 - 1979/1/12
N2 - Antireflux surgery was performed in five patients with vesicoureteral reflux at a time when renal insufficiency was present. Notable proteinuria was present in four of the patients, and a kidney biopsy specimen showed glomerular lesions in one. Despite the eradication of reflux and of infection, all five patients continued to have progressive renal insufficiency culminating in renal failure. Vesicoureteral reflux nephropathy may include a glomerulopathy leading to progressive glomerular sclerosis. Antireflux surgery would not alter this ongoing process and therefore would not halt progressive renal failure.
AB - Antireflux surgery was performed in five patients with vesicoureteral reflux at a time when renal insufficiency was present. Notable proteinuria was present in four of the patients, and a kidney biopsy specimen showed glomerular lesions in one. Despite the eradication of reflux and of infection, all five patients continued to have progressive renal insufficiency culminating in renal failure. Vesicoureteral reflux nephropathy may include a glomerulopathy leading to progressive glomerular sclerosis. Antireflux surgery would not alter this ongoing process and therefore would not halt progressive renal failure.
UR - http://www.scopus.com/inward/record.url?scp=0018788386&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018788386&partnerID=8YFLogxK
U2 - 10.1001/jama.1979.03290280040025
DO - 10.1001/jama.1979.03290280040025
M3 - Article
C2 - 758514
AN - SCOPUS:0018788386
VL - 241
SP - 160
EP - 162
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
SN - 0098-7484
IS - 2
ER -