TY - JOUR
T1 - Invasive Right Ventricular Pressure-Volume Analysis
T2 - Basic Principles, Clinical Applications, and Practical Recommendations
AU - Brener, Michael I.
AU - Masoumi, Amirali
AU - Ng, Vivian G.
AU - Tello, Khodr
AU - Bastos, Marcelo B.
AU - Cornwell, William K.
AU - Hsu, Steven
AU - Tedford, Ryan J.
AU - Lurz, Philipp
AU - Rommel, Karl Philipp
AU - Kresoja, Karl Patrik
AU - Nagueh, Sherif F.
AU - Kanwar, Manreet K.
AU - Kapur, Navin K.
AU - Hiremath, Gurumurthy
AU - Sarraf, Mohammad
AU - Van Den Enden, Antoon J.M.
AU - Van Mieghem, Nicolas M.
AU - Heerdt, Paul M.
AU - Hahn, Rebecca T.
AU - Kodali, Susheel K.
AU - Sayer, Gabriel T.
AU - Uriel, Nir
AU - Burkhoff, Daniel
N1 - Publisher Copyright:
© 2022 Lippincott Williams and Wilkins. All rights reserved.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Right ventricular pressure-volume (PV) analysis characterizes ventricular systolic and diastolic properties independent of loading conditions like volume status and afterload. While long-considered the gold-standard method for quantifying myocardial chamber performance, it was traditionally only performed in highly specialized research settings. With recent advances in catheter technology and more sophisticated approaches to analyze PV data, it is now more commonly used in a variety of clinical and research settings. Herein, we review the basic techniques for PV loop measurement, analysis, and interpretation with the aim of providing readers with a deeper understanding of the strengths and limitations of PV analysis. In the second half of the review, we detail key scenarios in which right ventricular PV analysis has influenced our understanding of clinically relevant topics and where the technique can be applied to resolve additional areas of uncertainty. All told, PV analysis has an important role in advancing our understanding of right ventricular physiology and its contribution to cardiovascular function in health and disease.
AB - Right ventricular pressure-volume (PV) analysis characterizes ventricular systolic and diastolic properties independent of loading conditions like volume status and afterload. While long-considered the gold-standard method for quantifying myocardial chamber performance, it was traditionally only performed in highly specialized research settings. With recent advances in catheter technology and more sophisticated approaches to analyze PV data, it is now more commonly used in a variety of clinical and research settings. Herein, we review the basic techniques for PV loop measurement, analysis, and interpretation with the aim of providing readers with a deeper understanding of the strengths and limitations of PV analysis. In the second half of the review, we detail key scenarios in which right ventricular PV analysis has influenced our understanding of clinically relevant topics and where the technique can be applied to resolve additional areas of uncertainty. All told, PV analysis has an important role in advancing our understanding of right ventricular physiology and its contribution to cardiovascular function in health and disease.
KW - heart failure
KW - hemodynamics
KW - pulmonary circulation
KW - ventricular function, right
KW - Ventricular Function, Left/physiology
KW - Ventricular Function, Right/physiology
KW - Heart Ventricles/physiopathology
KW - Humans
KW - Stroke Volume/physiology
KW - Hemodynamics/physiology
KW - Heart Failure/physiopathology
KW - Ventricular Dysfunction, Right/physiopathology
KW - Ventricular Pressure/physiology
UR - https://www.scopus.com/pages/publications/85123812896
UR - https://www.scopus.com/inward/citedby.url?scp=85123812896&partnerID=8YFLogxK
U2 - 10.1161/CIRCHEARTFAILURE.121.009101
DO - 10.1161/CIRCHEARTFAILURE.121.009101
M3 - Review article
C2 - 34963308
AN - SCOPUS:85123812896
SN - 1941-3289
VL - 15
SP - E009101
JO - Circulation: Heart Failure
JF - Circulation: Heart Failure
IS - 1
ER -