Introduction and Overview of Technological Advances and Predictive Assays

K. S. Ramos; Q. He; H. Gao

doi:10.1016/B978-0-08-046884-6.00235-9

Introduction and Overview of Technological Advances and Predictive Assays

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Abstract

The goal of this chapter is to introduce modern technologies in molecular toxicology, which have the power to transform the design, execution, and interpretation of toxicology studies. Toxicologists have begun to integrate systems biology approaches into toxicology studies in efforts to elucidate the role of mRNA, protein, and metabolites in toxicity. As a result, the predictive value of data generated in the future has the potential to greatly amplify current practices.

Original language	English (US)
Title of host publication	Cellular and Molecular Toxicology
Publisher	Elsevier
Pages	623-640
Number of pages	18
Volume	2
ISBN (Print)	9780080468686
DOIs	https://doi.org/10.1016/B978-0-08-046884-6.00235-9
State	Published - Aug 12 2010

Keywords

Bioinformatics
Data mining
ESTs
Proteomics
Transcript profiling

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-08-046884-6.00235-9

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AU - He, Q.

AU - Gao, H.

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N2 - The goal of this chapter is to introduce modern technologies in molecular toxicology, which have the power to transform the design, execution, and interpretation of toxicology studies. Toxicologists have begun to integrate systems biology approaches into toxicology studies in efforts to elucidate the role of mRNA, protein, and metabolites in toxicity. As a result, the predictive value of data generated in the future has the potential to greatly amplify current practices.

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KW - Bioinformatics

KW - Data mining

KW - ESTs

KW - Proteomics

KW - Transcript profiling

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DO - 10.1016/B978-0-08-046884-6.00235-9

M3 - Chapter

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SN - 9780080468686

VL - 2

SP - 623

EP - 640

BT - Cellular and Molecular Toxicology

PB - Elsevier

ER -

Introduction and Overview of Technological Advances and Predictive Assays

Abstract

Keywords

ASJC Scopus subject areas

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