Intranasal immunization of the combined Lipooligosaccharide conjugates protects mice from the challenges with three serotypes of Moraxella catarrhalis

Agriculture & Biology

• lipooligosaccharides 96%
• Moraxella catarrhalis 88%
• immunization 60%
• serotypes 52%
• mice 35%
• vaccines 23%
• lungs 21%
• blood serum 10%
• intranasal administration 10%
• immunoglobulin A 9%
• interleukin-12 9%
• interleukin-4 8%
• interferons 7%
• cell-mediated immunity 7%
• humoral immunity 7%
• cross reaction 6%
• plate count 6%
• cytokines 6%
• inflammation 6%
• transmission electron microscopy 6%
• antiserum 5%
• antibodies 4%
• pathogens 4%
• infection 3%
• methodology 1%

Medicine & Life Sciences

• lipid-linked oligosaccharides 93%
• Moraxella catarrhalis 82%
• Serogroup 55%
• Immunization 51%
• Moraxellaceae Infections 13%
• Nose 10%
• Lung 10%
• Vaccines 10%
• Serum 9%
• Combined Vaccines 9%
• Intranasal Administration 8%
• Conjugate Vaccines 8%
• Bacterial Load 7%
• Humoral Immunity 7%
• Interleukin-12 6%
• Transmission Electron Microscopy 6%
• Cellular Immunity 6%
• Immunoglobulin A 6%
• Interleukin-4 6%
• Interferons 6%
• Pneumonia 5%
• Immunoglobulin G 5%
• Cytokines 4%
• Antibodies 3%
• Control Groups 3%

Chemistry

• Lipooligosaccharide 100%
• Intranasal 98%
• Nasal 20%
• Strain 15%
• Clearance 8%
• Transmission Electron Microscopy 4%