Intracranial dual-mode IVUS transducer for image-guided brain therapypreliminary experiments

Carl D. Herickhoff, Patrick D. Wolf, S. W. Smith, Gerald A. Grant, Gavin W. Britz, Christy M. Wilson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

In this study, we investigated the feasibility of using 3.5-Fr IVUScatheters for minimally-invasive, image-guided hyperthermia treatment of tumorsin the brain. Feasibility is demonstrated in two ways: 1) by fitting a 3.5-FrIVUS catheter with a 5 × 0.5 × 0.22 mm PZT-4 transducer for 9-MHzimaging, and 2) by testing an identical transducer for therapy potential with3.3-MHz CW excitation. The imaging transducer's performance was compared to a9-Fr, 9-MHz ICE catheter as a gold standard, visualizing a 2.5-cm cyst phantomand a postmortem ovine brain. The therapy transducer was able to maintain apower output of 700 mW, achieving a temperature rise of 19°C at a depth of1.5 mm in excised brain tumor tissue.

Original languageEnglish (US)
Title of host publication2010 IEEE International Ultrasonics Symposium, IUS 2010
Pages1502-1505
Number of pages4
DOIs
StatePublished - Dec 1 2010
Event2010 IEEE International Ultrasonics Symposium, IUS 2010 - San Diego, CA, United States
Duration: Oct 11 2010Oct 14 2010

Other

Other2010 IEEE International Ultrasonics Symposium, IUS 2010
CountryUnited States
CitySan Diego, CA
Period10/11/1010/14/10

Keywords

  • dual-mode catheter transducer
  • intravascular ultrasound
  • ultrasoundhyperthermia

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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