TY - JOUR
T1 - Intracranial aneurysms
T2 - Review of current treatment options and outcomes
AU - Seibert, Brad
AU - Tummala, Ramachandra P.
AU - Chow, Ricky
AU - Faridar, Alireza
AU - Mousavi, Seyed A.
AU - Divani, Afshin A.
PY - 2011
Y1 - 2011
N2 - Intracranial aneurysms are present in roughly 5% of the population, yet most are often asymptomatic and never detected. Development of an aneurysm typically occurs during adulthood, while formation and growth are associated with risk factors such as age, hyper-tension, pre-existing familial conditions, and smoking. Subarachnoid hemorrhage, the most common presentation due to aneurysm rupture, represents a serious medical condition often leading to severe neurological deficit or death. Recent technological advances in imag-ing modalities, along with increased understanding of natural history and prevalence of aneurysms, have increased detection of asymptomatic unruptured intracranial aneurysms (UIA). Studies reporting on the risk of rupture and outcomes have provided much insight, but the debate remains of how and when unruptured aneurysms should be managed. Treatment methods include two major intervention options: clipping of the aneurysm and endovascular methods such as coiling, stent-assisted coiling, and flow diversion stents. The studies reviewed here support the generalized notion that endovascular treatment of UIA provides a safe and effective alternative to surgical treatment.The risks associated with endovascular repair are lower and incur shorter hospital stays for appropriately selected patients. The endovascular treatment option should be considered based on factors such as aneurysm size, location, patient medical history, and operator experience.
AB - Intracranial aneurysms are present in roughly 5% of the population, yet most are often asymptomatic and never detected. Development of an aneurysm typically occurs during adulthood, while formation and growth are associated with risk factors such as age, hyper-tension, pre-existing familial conditions, and smoking. Subarachnoid hemorrhage, the most common presentation due to aneurysm rupture, represents a serious medical condition often leading to severe neurological deficit or death. Recent technological advances in imag-ing modalities, along with increased understanding of natural history and prevalence of aneurysms, have increased detection of asymptomatic unruptured intracranial aneurysms (UIA). Studies reporting on the risk of rupture and outcomes have provided much insight, but the debate remains of how and when unruptured aneurysms should be managed. Treatment methods include two major intervention options: clipping of the aneurysm and endovascular methods such as coiling, stent-assisted coiling, and flow diversion stents. The studies reviewed here support the generalized notion that endovascular treatment of UIA provides a safe and effective alternative to surgical treatment.The risks associated with endovascular repair are lower and incur shorter hospital stays for appropriately selected patients. The endovascular treatment option should be considered based on factors such as aneurysm size, location, patient medical history, and operator experience.
KW - Aneurysms
KW - Clipping
KW - Coiling
KW - Endovascular surgery
KW - Flow diversion
KW - Stents
KW - Subarachnoid hemorrhage
UR - http://www.scopus.com/inward/record.url?scp=84862945173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862945173&partnerID=8YFLogxK
U2 - 10.3389/fneur.2011.00045
DO - 10.3389/fneur.2011.00045
M3 - Article
C2 - 21779274
AN - SCOPUS:84862945173
SN - 1664-2295
VL - JUL
JO - Frontiers in Neurology
JF - Frontiers in Neurology
M1 - Article 40
ER -