Intra-arterial thrombin injection of an ascending aortic pseudoaneurysm complicated by transient ischemic attack and rescued with systemic abciximab

Peter H. Lin, Ruth L. Bush, Frank C. Tong, Elliot Chaikof, Louis G. Martin, Alan B. Lumsden

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Thrombin injection as a means of inducing thrombus formation has recently received wide attention as an alternative treatment for pseudoaneurysm. We present a case of a 67-year-old man in whom a large mycotic pseudoaneurysm developed in the ascending aorta because of sternal osteomyelitis and mediastinitis after coronary artery bypass grafting. Transcatheter intra-arterial thrombin injection was performed, and it successfully induced pseudoaneurysm thrombosis. However, the procedure was complicated by a sudden transient ischemic attack caused by thrombus propagation into the cerebral circulation. Complete thrombus dissolution in the cerebral circulation with the resolution of neurologic symptoms was achieved by means of intravenous abciximab.

Original languageEnglish (US)
Pages (from-to)939-942
Number of pages4
JournalJournal of Vascular Surgery
Volume34
Issue number5
DOIs
StatePublished - Nov 2001

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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