Intra-arterial Cisplatin Treatment of Adenoid Cystic Carcinoma

Roy B. Sessions, Daniel E. Lehane, Richard J.H. Smith, R. Nick Bryan, James Y. Suen

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Adenoid cystic carcinoma (ACC) is unique among salivary gland tumors in both its natural history and in its response to nonsurgical treatment methods (i.e., radiation and chemotherapy). The chemotherapeutic agent, cisplatin, seems to be unique in its ability to affect ACC. It might be that ACCs of the minor salivary glands are especially vulnerable to the intraarterial method of administering this drug, because there are accessible feeding vessels to most locations locations in which these tumors occur. We have treated four patients with advanced ACC with intrarterial cisplatin. The responses suggest that this method may be a useful adjunct in the management of this tumor both as a preoperative and as a palliatative measure.

Original languageEnglish (US)
Pages (from-to)221-224
Number of pages4
JournalArchives of Otolaryngology
Issue number4
StatePublished - Apr 1982

ASJC Scopus subject areas

  • Otorhinolaryngology


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