Intestinal ischemia after allogeneic stem cell transplantation: A report of four cases

L. Prochaska; J. Vacek; R. Madan; S. Abhyankar; S. Ganguly; J. P. McGuirk; T. L. Lin; O. S. Aljitawi

doi:10.1016/j.transproceed.2013.12.066

Intestinal ischemia after allogeneic stem cell transplantation: A report of four cases

L. Prochaska, J. Vacek, R. Madan, S. Abhyankar, S. Ganguly, J. P. McGuirk, T. L. Lin, O. S. Aljitawi

Houston Methodist

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Gastrointestinal ischemia after allogeneic bone marrow transplantation is a rare complication not well-described in the literature. Herein we retrospectively review charts of four patients who developed intestinal ischemia after allogeneic bone marrow transplantation at our institution. The patients were found to be predominately younger males who presented with nonspecific abdominal pain. Graft-versus-host disease was a common finding among all patients. Laboratory values suggestive of microangiopathy were present in two patients. Obesity and hypertriglyceridemia were cardiovascular risk factors found in these patients. The development of thrombotic microangiopathy and cardiovascular risk factors after allogeneic bone marrow transplantation may predispose patients to gastrointestinal ischemia and may portend a poor prognosis.

Original language	English (US)
Pages (from-to)	1536-1539
Number of pages	4
Journal	Transplantation Proceedings
Volume	46
Issue number	5
DOIs	https://doi.org/10.1016/j.transproceed.2013.12.066
State	Published - Jun 2014

ASJC Scopus subject areas

Surgery
Transplantation

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10.1016/j.transproceed.2013.12.066

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title = "Intestinal ischemia after allogeneic stem cell transplantation: A report of four cases",

abstract = "Gastrointestinal ischemia after allogeneic bone marrow transplantation is a rare complication not well-described in the literature. Herein we retrospectively review charts of four patients who developed intestinal ischemia after allogeneic bone marrow transplantation at our institution. The patients were found to be predominately younger males who presented with nonspecific abdominal pain. Graft-versus-host disease was a common finding among all patients. Laboratory values suggestive of microangiopathy were present in two patients. Obesity and hypertriglyceridemia were cardiovascular risk factors found in these patients. The development of thrombotic microangiopathy and cardiovascular risk factors after allogeneic bone marrow transplantation may predispose patients to gastrointestinal ischemia and may portend a poor prognosis.",

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AU - Prochaska, L.

AU - Vacek, J.

AU - Madan, R.

AU - Abhyankar, S.

AU - Ganguly, S.

AU - McGuirk, J. P.

AU - Lin, T. L.

AU - Aljitawi, O. S.

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AB - Gastrointestinal ischemia after allogeneic bone marrow transplantation is a rare complication not well-described in the literature. Herein we retrospectively review charts of four patients who developed intestinal ischemia after allogeneic bone marrow transplantation at our institution. The patients were found to be predominately younger males who presented with nonspecific abdominal pain. Graft-versus-host disease was a common finding among all patients. Laboratory values suggestive of microangiopathy were present in two patients. Obesity and hypertriglyceridemia were cardiovascular risk factors found in these patients. The development of thrombotic microangiopathy and cardiovascular risk factors after allogeneic bone marrow transplantation may predispose patients to gastrointestinal ischemia and may portend a poor prognosis.

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Intestinal ischemia after allogeneic stem cell transplantation: A report of four cases

Abstract

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