Interstitial stress and fluid pressure within a growing tumor

Malisa Sarntinoranont; Frank Rooney; Mauro Ferrari

doi:10.1114/1.1554923

Interstitial stress and fluid pressure within a growing tumor

Malisa Sarntinoranont, Frank Rooney, Mauro Ferrari

Research output: Contribution to journal › Article › peer-review

132 Scopus citations

Abstract

Based upon analysis fo the mechanical fields, a framework for modeling regions of vascular collapse within central regions of a solid tumor was developed. The collapse of vessels was a critical issue in the transport of nutrients, waste products, drugs, and other biological agents within the tumor. In addition, vessel collapse was thought to contribute to the development of hypoxic and necrotic regions observed in rapidly growing tumors.

Original language	English (US)
Pages (from-to)	327-335
Number of pages	9
Journal	Annals of Biomedical Engineering
Volume	31
Issue number	3
DOIs	https://doi.org/10.1114/1.1554923
State	Published - 2003

Keywords

Poroelastic
Residual stress
Soft tissue mechanics
Tumor

ASJC Scopus subject areas

Biomedical Engineering

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10.1114/1.1554923

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title = "Interstitial stress and fluid pressure within a growing tumor",

abstract = "Based upon analysis fo the mechanical fields, a framework for modeling regions of vascular collapse within central regions of a solid tumor was developed. The collapse of vessels was a critical issue in the transport of nutrients, waste products, drugs, and other biological agents within the tumor. In addition, vessel collapse was thought to contribute to the development of hypoxic and necrotic regions observed in rapidly growing tumors.",

keywords = "Poroelastic, Residual stress, Soft tissue mechanics, Tumor",

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AU - Rooney, Frank

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AB - Based upon analysis fo the mechanical fields, a framework for modeling regions of vascular collapse within central regions of a solid tumor was developed. The collapse of vessels was a critical issue in the transport of nutrients, waste products, drugs, and other biological agents within the tumor. In addition, vessel collapse was thought to contribute to the development of hypoxic and necrotic regions observed in rapidly growing tumors.

KW - Poroelastic

KW - Residual stress

KW - Soft tissue mechanics

KW - Tumor

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Interstitial stress and fluid pressure within a growing tumor

Abstract

Keywords

ASJC Scopus subject areas

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