Interleukin-21 is a critical regulator of CD4 and CD8 T cell survival during priming under interleukin-2 deprivation conditions

Keyphrases

• CD8+ T Cells 100%
• Interleukin-2 100%
• CD4 T Cells 100%
• Deprivation 100%
• Interleukin-21 (IL-21) 100%
• T Cell Survival 100%
• Signaling Pathway 25%
• CD4+ T Cells 25%
• T Cell Activation 16%
• T Cell Immune Response 16%
• Targeted Therapy 16%
• Common gamma Chain Cytokines 16%
• Therapeutic Target 8%
• Bcl-2 Expression 8%
• Mitochondrial Membrane Potential 8%
• CD4+ 8%
• T-cell Mediated 8%
• Activated T Cells 8%
• Early Events 8%
• Survival Factor 8%
• Anti-interleukin-1 8%
• Effective Control 8%
• Reduced Survival 8%
• T Cell Expansion 8%
• Soluble Factors 8%
• Janus Tyrosine Kinase 8%
• Cognate Receptors 8%
• Co-culture Assay 8%
• Transwell Co-culture 8%

Immunology and Microbiology

• Cell Survival 100%
• Cytotoxic T-Cell 100%
• T-Helper Cell 100%
• Interleukin 2 100%
• Interleukin 21 100%
• Cytokine 33%
• T Cell 33%
• Immune Response 16%
• T Cell Activation 16%
• Common Gamma Chain 16%
• Secretion (Process) 8%
• Coculture 8%
• Cell Expansion 8%
• Tyrosine 8%
• Neutralization 8%
• Bcl-2 8%
• Mitochondrial Membrane Potential 8%
• Survival Factor 8%