Interaction of human plasma apolipoproteins and phospholipids. Semi-quantitative studies using polyacrylamide gel electrophoresis

J. S.K. David; G. R. Thompson; Antonio Gotto; J. D. Morrisett

doi:10.1016/0005-2760(75)90170-8

Interaction of human plasma apolipoproteins and phospholipids. Semi-quantitative studies using polyacrylamide gel electrophoresis

J. S.K. David, G. R. Thompson, Antonio Gotto, J. D. Morrisett

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The lipid-binding capacities of three human serum apolipoproteins (apoA-I, apoA-II and apoC-III₂) have been compared by polyacrylamide gel electrophoresis. Using ¹²⁵1-labeled apolipoproteins and ¹⁴ C-labeled lysophosphatidylcholine and phosphatidylcholine, the order of binding for both of these lipids was apoA-II > apoC-III₂ > apoA-I.

Original language	English (US)
Pages (from-to)	72-83
Number of pages	12
Journal	Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism
Volume	398
Issue number	1
DOIs	https://doi.org/10.1016/0005-2760(75)90170-8
State	Published - Jul 22 1975

ASJC Scopus subject areas

Biophysics
Biochemistry
Endocrinology

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10.1016/0005-2760(75)90170-8

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title = "Interaction of human plasma apolipoproteins and phospholipids. Semi-quantitative studies using polyacrylamide gel electrophoresis",

abstract = "The lipid-binding capacities of three human serum apolipoproteins (apoA-I, apoA-II and apoC-III2) have been compared by polyacrylamide gel electrophoresis. Using 1251-labeled apolipoproteins and 14 C-labeled lysophosphatidylcholine and phosphatidylcholine, the order of binding for both of these lipids was apoA-II > apoC-III2 > apoA-I.",

author = "David, \{J. S.K.\} and Thompson, \{G. R.\} and Antonio Gotto and Morrisett, \{J. D.\}",

note = "Funding Information: The help of MS Debbie Mason in preparing the manuscript and the technical assistanceo f Mrs Nancy Yen is gratefully acknow!edged. This work was supported by a grant from the National Heart and Lung Institute for a Specialized Center of Research in Atherosclerosis (HL-14194), by a Lipid Research Clinic contract (71-2156), and by an NIH General Clinical Research Center grant (RR-00350). (TBTGA). J.D.M. is an Established Investigator of the American Heart Association. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1975",

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doi = "10.1016/0005-2760(75)90170-8",

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T1 - Interaction of human plasma apolipoproteins and phospholipids. Semi-quantitative studies using polyacrylamide gel electrophoresis

AU - David, J. S.K.

AU - Thompson, G. R.

AU - Gotto, Antonio

AU - Morrisett, J. D.

N1 - Funding Information: The help of MS Debbie Mason in preparing the manuscript and the technical assistanceo f Mrs Nancy Yen is gratefully acknow!edged. This work was supported by a grant from the National Heart and Lung Institute for a Specialized Center of Research in Atherosclerosis (HL-14194), by a Lipid Research Clinic contract (71-2156), and by an NIH General Clinical Research Center grant (RR-00350). (TBTGA). J.D.M. is an Established Investigator of the American Heart Association. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1975/7/22

Y1 - 1975/7/22

N2 - The lipid-binding capacities of three human serum apolipoproteins (apoA-I, apoA-II and apoC-III2) have been compared by polyacrylamide gel electrophoresis. Using 1251-labeled apolipoproteins and 14 C-labeled lysophosphatidylcholine and phosphatidylcholine, the order of binding for both of these lipids was apoA-II > apoC-III2 > apoA-I.

AB - The lipid-binding capacities of three human serum apolipoproteins (apoA-I, apoA-II and apoC-III2) have been compared by polyacrylamide gel electrophoresis. Using 1251-labeled apolipoproteins and 14 C-labeled lysophosphatidylcholine and phosphatidylcholine, the order of binding for both of these lipids was apoA-II > apoC-III2 > apoA-I.

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IS - 1

ER -

Interaction of human plasma apolipoproteins and phospholipids. Semi-quantitative studies using polyacrylamide gel electrophoresis

Abstract

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