Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: Critical role of p38MAPK

Keyphrases

• Apoptotic Effect 100%
• Growth Factors 100%
• Insulin-like 100%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 100%
• Curcumin 100%
• Progastrin 100%
• Intestinal Epithelial Cells 80%
• Insulin-like Growth Factor 2 (IGF2) 53%
• Inhibitory Effect 20%
• Inhibitory Potency 20%
• MAPK Inhibitors 13%
• Hyperproliferation 13%
• Cell-to-cell 6%
• Overexpressing 6%
• Tumor 6%
• Dose Effect 6%
• Risk Factors 6%
• Protective Effect 6%
• Phosphorylation 6%
• ERK Phosphorylation 6%
• Antiproliferative Activity 6%
• Paracrine 6%
• Colon Adenocarcinoma 6%
• Hyperproliferative 6%
• Human Colon Cancer Cell Line 6%
• Caco-2 Cells 6%
• C-Src 6%
• Caco-2 6%

Biochemistry, Genetics and Molecular Biology

• Insulin-Like Growth Factor 2 100%
• Insulin-Like Growth Factor 100%
• Colon 25%
• Growth Factor 25%
• Wild Type 12%
• Cancer Cell 12%
• Carcinogenesis 12%
• Antiproliferative Activity 12%
• Oncogene Src 12%

Immunology and Microbiology

• Somatomedin B 100%
• Somatomedin 100%
• Growth Factor 25%
• Wild Type 12%
• Colon 12%
• Antiproliferative Activity 12%
• Oncogene Src 12%
• Colon Cancer Cell Line 12%
• Intestinal Cell Line 12%