Instability of the expanded (CTG)(n) repeats in the myotonin protein kinase gene in cultured lymphoblastoid cell lines from patients with myotonic dystrophy

Keyphrases

• Protein Kinase 100%
• Lymphoblastoid Cell Lines 100%
• Myotonic Dystrophy 100%
• Repeat Size 100%
• Somatic Instability 50%
• DM Patients 50%
• 3′-untranslated Region (3′-UTR) 25%
• Southern Blotting 25%
• Germ Cells 25%
• Cellular Origin 25%
• Small Changes 25%
• Size Heterogeneity 25%
• Blood Cells 25%
• Mutation Type 25%
• Repeat Region 25%
• PCR Method 25%
• Trinucleotide Repeats 25%
• Multiple Steps 25%
• Rare mutation 25%
• Single-cell PCR 25%
• Frequent mutation 25%
• Expanded Repeats 25%
• Limiting Dilution 25%

Biochemistry, Genetics and Molecular Biology

• Allele 100%
• Myotonin-Protein Kinase 100%
• Southern Blotting 33%
• Untranslated Region 33%
• Cell Cycle 33%
• Dilution 33%
• Germline 33%
• Germ Cell 33%
• Gaussian Distribution 33%
• Trinucleotide Repeat Expansion 33%