Innate immunity and epigenetic plasticity in cellular reprogramming

John P. Cooke, Nazish Sayed, Jieun Lee, Wing Tak Wong

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Somatic cells can be reprogrammed to express the features of pluripotent cells, in that they can be differentiated into all three germ layers, and that they have the ability to replicate indefinitely. Recent studies suggest that the efficient induction of pluripotency requires the activation of innate immunity.

Original languageEnglish (US)
Pages (from-to)89-91
Number of pages3
JournalCurrent Opinion in Genetics and Development
StatePublished - Oct 1 2014

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology


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