Inherited combined deficiency of factor V and factor VIII: Report of a case with normal factor VIII antigen and ristocetin‐induced platelet aggregation

P. L. Cimo, J. L. Moake, M. F. Gonzalez, E. A. Natelson, K. R. Fox

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

A patient with inherited combined deficiency of factor V and factor VIII is reported, who demonstrated normal levels of factor VIII antigen and plasma cofactor for ristocetin-induced platelet aggregation. The relationship of this condition to classical hemophilia and von Willebrand's disease is discussed. The data presented suggest that multiple loci on at least 2 chromosomes are necessary for the normal expression of factor VIII activity.

Original languageEnglish (US)
Pages (from-to)385-391
Number of pages7
JournalAmerican Journal of Hematology
Volume2
Issue number4
DOIs
StatePublished - 1977

Keywords

  • blood coagulation disorders
  • factor V deficiency
  • hemophilia

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Inherited combined deficiency of factor V and factor VIII: Report of a case with normal factor VIII antigen and ristocetin‐induced platelet aggregation'. Together they form a unique fingerprint.

Cite this