Influence of nanophase titania topography on bacterial attachment and metabolism

Margaret R. Park, Michelle K. Banks, Bruce Applegate, Thomas J. Webster

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Surfaces with nanophase compared to conventional (ornanometer smooth) topographies are known to have different properties of area, charge, and reactivity. Previously published research indicates that the attachment of certain bacteria (such as Pseudomonas fluorescens 5RL) is higher on surfaces with nanophase compared to conventional topographies, however, their effect on bacterial metabolism is unclear. Results presented here show that the adhesion of Pseudomonas fluorescens 5RL and Pseudomonas putida TVA8 was higher on nanophase than conventional titania. Importantly, in terms of metabolism, bacteria attached to the nanophase surfaces had higher bioluminescence rates than on the conventional surfaces under all nutrient conditions. Thus, the results from this study show greater select bacterial metabolism on nanometer than conventional topographies, critical results with strong consequences for the design of improved biosensors for bacteria detection.

Original languageEnglish (US)
Pages (from-to)497-504
Number of pages8
JournalInternational Journal of Nanomedicine
Volume3
Issue number4
StatePublished - 2008

Keywords

  • Attachment
  • Bacteria
  • Metabolism
  • Nanophase
  • Topography

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Pharmaceutical Science
  • Drug Discovery
  • Organic Chemistry

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