Inflammatory pseudotumor of the pancreas

Steven H. Kroft, Steven J. Stryker, Jane N. Winter, Gulchi Ergun, M. Sambasiva Rao

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

We describe a rare example of inflammatory pseudotumor of the pancreas in a 42-yr-old woman, which developed following chemotherapy for lymphoma of the uterine cervix. The patient had developed fatigue, weight loss abdominal pain, and anemia; abdominal CT scan showed a large mass in the pancreas. Examination of the resected specimen revealed a fleshy, well-circumscribed, 7-cm mass., Histologically, there was a hypocellular to moderately hypercellular, bland spindle-cell proliferation admixed with a prominent infiltrate of lymphocytes, histiocytes, and plasma cells. The spindle cells were vimentin positive but negative for muscle markers; electron microscopy revealed only fibroblastic cells. DNA analysis revealed a diploid population with low S-phase fraction. The patient was well at 6-mo follow-up. It is important for the pathologist to be aware of the existence of this entity in unusual locations such as the pancreas so as to avoid a mistaken diagnosis of malignancy.

Original languageEnglish (US)
Pages (from-to)277-283
Number of pages7
JournalInternational Journal of Pancreatology
Volume18
Issue number3
DOIs
StatePublished - Dec 1995

Keywords

  • inflammatory
  • Pancreas
  • pseudotumor

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology
  • Endocrinology

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