Abstract
Since the fibrinolytic system of the swine is close to that of human, the use of a swine model may assume increasing prominence in future studies of thrombosis. Swine platelets were labeled with 111In in a modified Tyrode's solution, suspended in plasma, then injected intravenously into swine. The average radioactivity incorporated into the platelets was 44 +/- 27%. The recovery of labeled platelets at 5 minutes post-injection was 81.7 +/- 5.3%. The platelets retained their label throughout their life span. The survival of 111In-platelets was described by a one component exponential equation, with a life span of 157.9 +/- 25.3 hrs.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 444-447 |
| Number of pages | 4 |
| Journal | Laboratory animal science |
| Volume | 38 |
| Issue number | 4 |
| State | Published - Jan 1 1988 |
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)