Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice

Keyphrases

• Gene-deficient Mice 100%
• Liver Fibrosis 100%
• Carbon Tetrachloride 100%
• Fibroblast Growth Factor Receptor 4 (FGFR4) 100%
• Induced Liver Injury 100%
• Liver 30%
• Cytochrome P450 2E1 (CYP2E1) 20%
• Cholesterol 10%
• Fibroblast Growth Factor Receptor 1 (FGFR1) 10%
• Liver Injury 10%
• Cytochrome P450 (CYP450) 10%
• Protein Level 10%
• MRNA Level 10%
• Germ Cells 10%
• Rodents 10%
• Cholesterol Metabolism 10%
• Cellularity 10%
• Metabolic Function 10%
• Acute Exposure 10%
• Fibrosis 10%
• Hepatocytes 10%
• Insults 10%
• Receptor Gene 10%
• Rate-limiting Enzyme 10%
• Chronic Exposure 10%
• Liver-specific 10%
• Liver Mass 10%
• Bile Acid Metabolism 10%
• Severe Fibrosis 10%
• Elevated Cholesterol 10%
• Mature Hepatocytes 10%
• Acute Liver Injury 10%
• Chronic Liver Injury 10%

Medicine and Dentistry

• Fibroblast Growth Factor Receptor 4 100%
• Carbon Tetrachloride-Induced Liver Injury 100%
• Carbon Tetrachloride-Induced Liver Fibrosis 100%
• Carbon Tetrachloride 60%
• Fibrosis 20%
• Hepatocyte 20%
• CYP2E1 20%
• Liver Injury 20%
• Messenger RNA 10%
• Downregulation 10%
• Cytochrome P450 10%
• Hypercholesterolemia 10%
• Cholesterol Metabolism 10%
• Germ Cell 10%
• Receptor Gene 10%
• Long Term Exposure 10%
• Fibroblast Growth Factor Receptor 10%
• Bile Acid Synthesis 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Fibroblast Growth Factor Receptor 4 100%
• Carbon Tetrachloride-Induced Liver Injury 100%
• Carbon Tetrachloride-Induced Liver Fibrosis 100%
• Carbon Tetrachloride 60%
• Liver Injury 20%
• Fibrosis 20%
• CYP2E1 20%
• Messenger RNA 10%
• Cytochrome P450 10%
• Hypercholesterolemia 10%
• Bile Acid 10%
• Long Term Exposure 10%
• Fibroblast Growth Factor Receptor 10%