Increase in invasive Streptococcus pyogenes M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023

Stephen B. Beres, Randall J. Olsen, S. Wesley Long, Ross Langley, Thomas Williams, Helga Erlendsdottir, Andrew Smith, Karl G. Kristinsson, James M. Musser

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Group A Streptococcus isolates of the recently described M1UK clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1UK variant responsible for almost all recent M1 infections in Iceland.

Original languageEnglish (US)
JournalEurosurveillance
Volume29
Issue number13
DOIs
StatePublished - Mar 28 2024

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health
  • Virology

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