TY - JOUR
T1 - Incidence and risk for mood and anxiety disorders in a representative sample of Ohio army national guard members, 2008–2012
AU - Fink, David S.
AU - Chen, Qixuan
AU - Liu, Yutao
AU - Tamburrino, Marijo B.
AU - Liberzon, Israel
AU - Shirley, Edwin
AU - Fine, Thomas
AU - Cohen, Gregory H.
AU - Galea, Sandro
AU - Calabrese, Joseph R.
N1 - Funding Information:
This article was supported by National Institute on Drug Abuse grant #T32DA031099 [DSF]. This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs through the Joint Warfighter Medical Research Program under Award No. W81XWH-15-1-0080, W81XWH-07-1-0409, and W81XWH-10-1-0579 [DSF, MTB, IL, PC, GHC, LS, ES, TG, ND, TF, PLR, JRC, SG]. The U.S. Army Medical Research Acquisition Activity, 820 Chandler Street, Fort Detrick MD 21702-5014, is the awarding and administering acquisition office. Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the Department of Defense. The funding organization reviewed and approved the study but had no role in the design and conduct of the study; collection, management, analysis, or interpretation of the data; or preparation of the article. The informatics support for this research was provided by the Michigan State University Clinical and Translation Sciences Institute, through its Biomedical Research Informatics Core. The Institutional Review Boards at the University Hospitals Case Medical Center and University of Toledo approved all study methods.
Publisher Copyright:
© 2016 Association of Schools and Programs of Public Health.
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Objective. We investigated the incidence of first-onset psychiatric disorders among Ohio Army National Guard members and the sociodemographic and military factors associated with these incident disorders. We aimed to identify potential risk factors and mitigating factors for a range of psychiatric disorders in a representative military sample. Methods. We analyzed data on a representative sample of 528 Ohio Army National Guard members who were assessed in person annually for first-onset psychiatric disorders from 2008 through 2012 using structured clinical interviews. We used a multivariable discrete-time Cox proportional hazard model to determine risk factors of first-onset anxiety or mood disorders. Results. The annualized incidence rate of any first-onset psychiatric disorder was 9.8 per 100 person-years at risk. Alcohol use disorder and major depressive disorder had the highest incidence rates among the unique disorders under study (5.0 and 4.2 per 100 person-years at risk, respectively). We found an association between respondents endorsing past-year deployment and a 29% increase in the risk of incident anxiety or mood disorder, whereas the past-year experience of any non-deployment traumatic event was associated with a 32% increase in risk of incident anxiety or mood disorder. Conclusion. Soldiers experience a substantial burden of first-onset alcohol use disorder and major depressive disorder annually; the experience of non-deployment–related traumatic events contributes substantially to increasing risk, suggesting that any effort aimed at mitigating mood and anxiety disorders in this population must consider the soldier’s life experience and military experience.
AB - Objective. We investigated the incidence of first-onset psychiatric disorders among Ohio Army National Guard members and the sociodemographic and military factors associated with these incident disorders. We aimed to identify potential risk factors and mitigating factors for a range of psychiatric disorders in a representative military sample. Methods. We analyzed data on a representative sample of 528 Ohio Army National Guard members who were assessed in person annually for first-onset psychiatric disorders from 2008 through 2012 using structured clinical interviews. We used a multivariable discrete-time Cox proportional hazard model to determine risk factors of first-onset anxiety or mood disorders. Results. The annualized incidence rate of any first-onset psychiatric disorder was 9.8 per 100 person-years at risk. Alcohol use disorder and major depressive disorder had the highest incidence rates among the unique disorders under study (5.0 and 4.2 per 100 person-years at risk, respectively). We found an association between respondents endorsing past-year deployment and a 29% increase in the risk of incident anxiety or mood disorder, whereas the past-year experience of any non-deployment traumatic event was associated with a 32% increase in risk of incident anxiety or mood disorder. Conclusion. Soldiers experience a substantial burden of first-onset alcohol use disorder and major depressive disorder annually; the experience of non-deployment–related traumatic events contributes substantially to increasing risk, suggesting that any effort aimed at mitigating mood and anxiety disorders in this population must consider the soldier’s life experience and military experience.
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U2 - 10.1177/0033354916662221
DO - 10.1177/0033354916662221
M3 - Article
C2 - 27453607
AN - SCOPUS:84977123773
SN - 0033-3549
VL - 131
SP - 614
EP - 622
JO - Public Health Reports
JF - Public Health Reports
IS - 4
ER -