In vivo labeling and enumeration of circulating tumor cells with a folate-receptor targeted molecular probe

Joshua Pace, Fernando Ivich, Roshani A. Patil, Srinivasarao Madduri, Mansoor M. Amiji, Philip S. Low, Mark Niedre

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We used a folate-receptor targeted fluorescent molecular probe to label circulating tumor cells directly in the bloodstream in mouse metastasis models. We used a new diffuse light-based optical instrument to non-invasively detect and count them.

Original languageEnglish (US)
Title of host publicationOptical Molecular Probes, Imaging and Drug Delivery, OMP 2021
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)9781557528209
StatePublished - 2021
EventOptical Molecular Probes, Imaging and Drug Delivery, OMP 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 - Virtual, Online, United States
Duration: Apr 12 2021Apr 16 2021

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceOptical Molecular Probes, Imaging and Drug Delivery, OMP 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021
Country/TerritoryUnited States
CityVirtual, Online
Period4/12/214/16/21

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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