TY - JOUR
T1 - In-vivo imaging of carotid plaque neoangiogenesis with contrast-enhanced harmonic ultrasound
AU - Papaioannou, Theodore G.
AU - Vavuranakis, Manolis
AU - Androulakis, Aristides
AU - Lazaros, George
AU - Kakadiaris, Ioannis
AU - Vlaseros, Ioannis
AU - Naghavi, Morteza
AU - Kallikazaros, Ioannis
AU - Stefanadis, Christodoulos
PY - 2009/5/29
Y1 - 2009/5/29
N2 - We describe a case where a mild carotid atherosclerotic plaque was assessed by contrast enhanced harmonic ultrasonography and image analysis. Quantitative indices of plaque echogenicity were determined prior and after the injection of microbubbles. Changes in plaque echogenicity were detected possibly due to the flow of microbubbles through vasa vasorum within the plaque and at the plaque base at the adventitial level. Future histological studies remain to be done to link the presence and the extent of plaque and adventitial neovascularization with the visual and quantitative findings derived by contrast enhanced harmonic ultrasound and image analysis.
AB - We describe a case where a mild carotid atherosclerotic plaque was assessed by contrast enhanced harmonic ultrasonography and image analysis. Quantitative indices of plaque echogenicity were determined prior and after the injection of microbubbles. Changes in plaque echogenicity were detected possibly due to the flow of microbubbles through vasa vasorum within the plaque and at the plaque base at the adventitial level. Future histological studies remain to be done to link the presence and the extent of plaque and adventitial neovascularization with the visual and quantitative findings derived by contrast enhanced harmonic ultrasound and image analysis.
KW - Harmonic ultrasound
KW - Microbubbles
KW - Neoangiogenesis
KW - Vasa vasorum
KW - Vulnerable plaque
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U2 - 10.1016/j.ijcard.2008.01.020
DO - 10.1016/j.ijcard.2008.01.020
M3 - Article
C2 - 18495267
AN - SCOPUS:67349267851
VL - 134
SP - e110-e112
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
IS - 3
ER -