In vivo imaging assessment of porous silicon

This chapter highlights the use of porous silicon (PSi)-based imaging agents with currently available imaging platforms. The intrinsic optical properties, the potential for surface modification as well as the high porosity available for bearing nested imaging contrast agents has made PSi an attractive material for in vivo imaging/diagnostic applications. The first part of the chapter gives a review of the mechanisms of the various imaging modalities available. The chapter then describes the various modifications of PSi that enable its potential application as an in vivo imaging tool.