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In-vivo fluorescence lifetime tomography for detection and quantification of programmed death ligand-1

Rahul Pal, Murali Krishnamoorthy, Aya Matsui, Satoru Morita, Hajime Taniguchi, Homan Kang, Hak Soo Choi, Dan G. Duda, Anand T.N. Kumar

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Cancer immunotherapy relies on PD-L1 expression, often assessed through immunohistochemistry, offering limited insights. In-vivo fluorescence lifetime (FLT) imaging, utilizing PD-L1-targeted probes, provides quantitative estimates of PD-L1 heterogeneity across tumors, showing promise for clinical translation of FLT imaging.

Original languageEnglish (US)
Title of host publicationOptical Tomography and Spectroscopy, OT and S 2024 in Proceedings Optica Biophotonics Congress
Subtitle of host publicationBiomedical Optics 2024, Translational, Microscopy, OCT, OTS, BRAIN - Part of Optica Biophotonics Congress: Biomedical Optics
PublisherOptical Society of America
ISBN (Electronic)9781957171340
DOIs
StatePublished - 2024
EventOptical Tomography and Spectroscopy, OT and S 2024 - Part of Optica Biophotonics Congress: Biomedical Optics - Fort Lauderdale, United States
Duration: Apr 7 2024 → Apr 10 2024

Publication series

NameOptical Tomography and Spectroscopy, OT and S 2024 in Proceedings Optica Biophotonics Congress: Biomedical Optics 2024, Translational, Microscopy, OCT, OTS, BRAIN - Part of Optica Biophotonics Congress: Biomedical Optics

Conference

ConferenceOptical Tomography and Spectroscopy, OT and S 2024 - Part of Optica Biophotonics Congress: Biomedical Optics
Country/TerritoryUnited States
CityFort Lauderdale
Period4/7/24 → 4/10/24

ASJC Scopus subject areas

  • General Computer Science
  • Space and Planetary Science
  • Control and Systems Engineering
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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