In vitro transfer of phosphatidylcholines and their ether analogs by a human and rat plasma exchange factor

Henry J. Pownall, Diane L.M. Hickson, Antonio M. Gotto, John B. Massey

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The phospholipid transfer properties of human and rat plasma have been studied using radiolabeled phosphatidylcholines (PCs) and diether PCs as well as a series of fluorescent PCs. The PC transfer activities of human and rat lipoprotein deficient sera are similar. Lipoprotein deficient rat serum transfers PC at a rate that is similar, if not identical, to the rate of transfer of the ether analogs of PC. These results suggest that PC ethers might be used to identify the nonhydrolytic metabolic routes of PCs.

Original languageEnglish (US)
Pages (from-to)452-457
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume119
Issue number2
DOIs
StatePublished - Mar 15 1984

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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