In situ detection of liver cancer biomarkers with atomic force microscopy at a single-molecule level

Bochong Tang, Min Li, Xiao Zhang, Jiaojiao Wang, Peng Xie, Yuliang Zhao, Zhongqing Wei

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

α-Fetoprotein (AFP), a surveillance biomarker of liver cancer, was directly detected via immunoassay at a singlemolecule level using in situ atomic force microscopy (AFM). AFM size measurements confirmed the successful capture of single AFP molecules by monoclonal antibody molecules on a one-to-one basis.

Original languageEnglish (US)
Pages (from-to)1154-1156
Number of pages3
JournalChemistry Letters
Volume42
Issue number10
DOIs
StatePublished - 2013

ASJC Scopus subject areas

  • Chemistry(all)

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