Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study

Gymama E. Slaughter; Erhard Bieberich; Gary E. Wnek; Kenneth J. Wynne; Anthony Guiseppi-Elie

doi:10.1021/la049192s

Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study

Gymama E. Slaughter, Erhard Bieberich, Gary E. Wnek, Kenneth J. Wynne, Anthony Guiseppi-Elie

Academic Institute

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.

Original language	English (US)
Pages (from-to)	7189-7200
Number of pages	12
Journal	Langmuir
Volume	20
Issue number	17
DOIs	https://doi.org/10.1021/la049192s
State	Published - Aug 17 2004

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

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10.1021/la049192s

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abstract = "The phenomena of neuron-to-electrode surface attachment NESA) via self-assembly of alkanethiol was investigated. The phenomena of hysteresis indicated cysteamine (CA) self-assembly monolayers (SAM) displays greater amphiphilic character than 11-amino-1-undecanethiol (11-AUT)-SAM. The tapping mode atomic force microscopy (AFM) also confirmed 6% increase and 22% decrease in surface roughness when compared to clean, unmodified and sputter-deposited gold. The results show that covalent immobilization of adhesion-promoting proteins enhanced NESA by tightly anchoring cells to electrode.",

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AU - Guiseppi-Elie, Anthony

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Improving neuron-to-electrode Surface attachment via alkanethiol self-assembly: An alternating current impedance study

Abstract

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