Improvement of erythema dyschromicum perstans using a combination of the 1,550-nm erbium-doped fractionated laser and topical tacrolimus ointment

Jon A. Wolfshohl, Elizabeth R.C. Geddes, Ashlyn B. Stout, Paul M. Friedman

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Background and Objective: Erythema dyschromicum perstans (EDP) is a cosmetically distressing, acquired pigmentary disorder of unknown etiology for which few successful therapies exist. Herein, we present the successful use of non-ablative fractional photothermolysis in combination with topical tacrolimus ointment. Study Design/Patients and Methods: A 35-year-old female with biopsy-confirmed EDP underwent a series of fractionated non-ablative treatment sessions utilizing the 1,550 nm erbium-doped fiber laser in combination with topical tacrolimus ointment over a period of 5 months. Results: The patient's EDP improved by greater than 75% and results were maintained at the 8-month follow-up visit. Conclusion: The combination of non-ablative fractional photothermolysis and topical tacrolimus ointment is a potential safe and effective therapeutic option for erythema dyschromicum perstans. Additional prospective, comparative studies are warranted. Lasers Surg. Med. 49:60–62, 2017.

Original languageEnglish (US)
Pages (from-to)60-62
Number of pages3
JournalLasers in Surgery and Medicine
Volume49
Issue number1
DOIs
StatePublished - Jan 1 2017

Keywords

  • ashy dermatosis
  • edp
  • erythema dyschromicum perstans
  • fraxel
  • laser
  • nonablative 1550 nm erbium-doped fractionated laser
  • pigment disorder
  • pigmentary disorder

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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