Improvement of erythema dyschromicum perstans using a combination of the 1,550-nm erbium-doped fractionated laser and topical tacrolimus ointment

Jon A. Wolfshohl, Elizabeth R C Geddes, Ashlyn B. Stout, Paul Friedman

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Background and Objective: Erythema dyschromicum perstans (EDP) is a cosmetically distressing, acquired pigmentary disorder of unknown etiology for which few successful therapies exist. Herein, we present the successful use of non-ablative fractional photothermolysis in combination with topical tacrolimus ointment. Study Design/Patients and Methods: A 35-year-old female with biopsy-confirmed EDP underwent a series of fractionated non-ablative treatment sessions utilizing the 1,550nm erbium-doped fiber laser in combination with topical tacrolimus ointment over a period of 5 months. Results: The patient's EDP improved by greater than 75% and results were maintained at the 8-month follow-up visit. Conclusion: The combination of non-ablative fractional photothermolysis and topical tacrolimus ointment is a potential safe and effective therapeutic option for erythema dyschromicum perstans. Additional prospective, comparative studies are warranted.

Original languageEnglish (US)
JournalLasers in Surgery and Medicine
DOIs
StateAccepted/In press - 2016

Keywords

  • Ashy dermatosis
  • Edp
  • Erythema dyschromicum perstans
  • Fraxel
  • Laser
  • Nonablative 1550nm erbium-doped fractionated laser
  • Pigment disorder
  • Pigmentary disorder

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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