Implementation of a hospital-wide EHR-integrated antibiotic challenge order set

Wesley Hoffmann; Shivani Patel; Shemual Tsai; Natalie Finch; Muhammad Yasser Alsafadi

doi:10.1017/ash.2025.10215

Implementation of a hospital-wide EHR-integrated antibiotic challenge order set

Wesley Hoffmann, Shivani Patel, Shemual Tsai, Natalie Finch, Muhammad Yasser Alsafadi

Research output: Contribution to journal › Article › peer-review

Abstract

We implemented an electronic health record-integrated order set to standardize direct antibiotic challenges for patients with reported antibiotic allergies across nine healthcare facilities. In the first year, 104 patients were challenged (79% oral; 39% two-step). Embedded antibiotic selection, dosage, monitoring parameters, reaction guidance, and rescue medications facilitated uptake by hospitalists and subspecialists.

Original language	English (US)
Article number	e286
Pages (from-to)	e286
Journal	Antimicrobial Stewardship and Healthcare Epidemiology
Volume	5
Issue number	1
DOIs	https://doi.org/10.1017/ash.2025.10215
State	Published - Oct 27 2025

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

Divisions

Infectious Disease

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10.1017/ash.2025.10215

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Implementation of a hospital-wide EHR-integrated antibiotic challenge order set

Abstract

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