Impact on Image Quality and Radiation Dose of Third-Generation Dual-Source Computed Tomography of the Coronary Arteries

Georg Apfaltrer, Dieter H. Szolar, Eric Wurzinger, Richard A.P. Takx, John Nance, Anja Dutschke, Sebastian Tschauner, Christian Loewe, Helmut Ringl, Erich Sorantin, Paul Apfaltrer

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


The aim of this study was to assess the image quality (IQ) and radiation dose of third-generation dual-source computed tomography (CT) coronary angiography (cCTA) in comparison with 64-slice single-source CT. This retrospective study included 140 patients (73 men, mean age 62 ± 11 years) with low-to-intermediate probability of coronary artery disease who underwent either third-generation dual-source cCTA using prospectively electrocardiography-triggered high-pitch spiral acquisition (n = 70) (group 1) or retrospective electrocardiography-gated cCTA on a 64-slice CT system (n = 70) (group 2). Contrast-to-noise and signal-to-noise ratios were measured within the aorta and coronary arteries. Subjective IQ was assessed using a 5-point Likert scale. Effective dose was estimated using specific conversion factors. The contrast-to-noise ratio of group 1 was significantly higher than group 2 at all levels (all p <0.001). Signal-to-noise ratio of group 1 was also significantly higher than group 2 (p <0.05), except for the distal left circumflex artery. Subjective IQ for group 1 was rated significantly better than for group 2 (median score [25th to 75th percentile]: 1 [1 to 2] vs 2 [2 to 3]; p <0.001). The median effective dose was 1.55 mSv (1.09 to 1.88) in group 1 versus 12.29 mSv (11.63 to 14.36) in group 2 (p <0.001) which corresponds to a mean radiation dose reduction of 87.4%. In conclusion, implementation of third-generation dual-source CT system for cCTA leads to improved IQ with significant radiation dose savings.

Original languageEnglish (US)
Pages (from-to)1156-1161
Number of pages6
JournalAmerican Journal of Cardiology
Issue number8
StatePublished - Apr 15 2017

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Impact on Image Quality and Radiation Dose of Third-Generation Dual-Source Computed Tomography of the Coronary Arteries'. Together they form a unique fingerprint.

Cite this